作者
Hironari Shiwaku, Hiroki Sato, Yuto Shimamura, Hirofumi Abe, Junya Shiota, Chiaki Sato, Masaki Ominami, Hiroyuki Sakae, Yoshitaka Hata, Hisashi Fukuda, Ryo Ogawa, Jun Nakamura, Tetsuya Tatsuta, Yuichiro Ikebuchi, Hiroshi Yokomichi, Suguru Hasegawa, Haruhiro Inoue
发表日期
2022/9
期刊
Endoscopy
卷号
54
期号
09
页码范围
839-847
出版商
Georg Thieme Verlag KG
简介
Background Gastroesophageal reflux disease (GERD) and reflux esophagitis remain problems after peroral endoscopic myotomy (POEM). This study aimed to elucidate the risk factors and long-term course of reflux esophagitis and symptomatic GERD after POEM.
Methods This multicenter cohort study involved 14 high volume centers. Overall, 2905 patients with achalasia-related esophageal motility disorders treated with POEM were analyzed for reflux esophagitis, severe reflux esophagitis (Los Angeles classification C or D), and symptomatic GERD.
Results Reflux esophagitis was diagnosed in 1886 patients (64.9 %). Age ≥ 65 years (risk ratio [RR] 0.85), male sex (RR 1.11), posterior myotomy (RR 1.12), esophageal myotomy > 10 cm (RR 1.12), and gastric myotomy > 2 cm (RR 1.17) were independently associated with reflux esophagitis. Severe reflux esophagitis was diagnosed in 219 patients (7 …
学术搜索中的文章
H Shiwaku, H Sato, Y Shimamura, H Abe, J Shiota… - Endoscopy, 2022