查看文章

Scaffolds and their features play a central role in tissue engineering; so this study is based on the production of a series of electrospun PHB/Chitosan/nBG nanocomposite scaffolds with 9 wt% polyhydroxybutyrate, 10, 15 and 20 wt% chitosan and 7.5, 10 and 15 wt% nanobioglass (nBG). Electrospinning process was performed with optimal conditions of spinning machine including voltage of 16 kV, syringe-collector spacing of 16 cm, and output rate of 1 µl per hour. The developed phases and the formation of chemical bonds between ceramic and polymer bands were studied through XRD and FTIR analyses. The FE-SEM and TEM analyses showed uniform morphology of nanofibers and dispersion of bioglass nanoparticles in the fiber structure. The presence of 10 wt% bioglass nanoparticles and 15 wt% chitosan increased the tensile strength of fibers to 3.42 MPa, which was about four times greater than …