作者
Anna Mrzljak, Petra Dinjar-Kujundzic, Mladen Knotek, Boris Kudumija, Mario Ilic, Marijana Gulin, Lada Zibar, Irena Hrstic, Zeljka Jurekovic, Branko Kolaric, Lorena Jemersic, Jelena Prpic, Morana Tomljenovic, Tatjana Vilibic-Cavlek
发表日期
2020/2
期刊
International urology and nephrology
卷号
52
期号
2
页码范围
371-378
出版商
Springer Netherlands
简介
Purpose
Data on the seroprevalence of hepatitis E virus (HEV) in heamodialysis (HD) patients are conflicting, ranging from 0 to 44%. The aim of this study was to determine the HEV seroprevalence and risk factors among HD patients in Croatia.
Methods
A total of 394 HD patients from six medical facilities in five Croatian cities (three sites in the continental and three sites in the coastal region) were tested for HEV IgM/IgG antibodies using an enzyme-linked immunosorbent assay. Additionally, all samples were tested for HEV RNA by RT-PCR. Sociodemographic data and risk factors were collected using a questionnaire.
Results
HEV IgG antibodies were detected in 110 (27.9%) patients. The seroprevalence varied significantly between dialysis centres, ranging from 5.2 to 43.4% (p = 0.001). HEV IgM antibodies were found in 0.04% of IgG positive patients. All patients tested negative for HEV RNA. Factors …
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