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This study examined whether the standard deviation (SD) values on the histogram measured in the picture archiving and communication system (PACS) views of an ultrasound (US) can be used as an index to determine the homogeneity or heterogeneity of a hepatic parenchymal echo. Patients (n = 202) underwent an abdominal US examination. One US unit was used with a convex (3 to 5 MHz) transducer. The echogenicity of the hepatic parenchyma was measured in four different regions-of-interest (ROIs) of the liver with all vessels, bile ducts and calcification being avoided. The SDs were calculated automatically on the histogram of the ROI in the PACS views. The echo patterns of the liver were classified into normal, fatty liver (FL) and chronic liver disease (CLD). The distribution of the SD calculated from the ROI histogram of these three groups was examined, and statistical analysis for multiple comparisons of …