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Introduction For centuries people have used plants for healing. Natural products have been used with varying success to cure and prevent diseases throughout history, and continue to provide mankind with new remedies. People often resort to traditional and other forms of complementary and alternative medicines for chronic conditions which do not respond well to conventional or modern drug treatments. Among these are neurological disorders such as anxiety, depression, epilepsy and pain. The World Health Organization (WHO) estimates that about 75 % of the world population primarily those of developing countries depend on traditional remedies (mainly herbs) for the healthcare of its people. Considering the great reliance on traditional medicinal plants for treatment of diseases and the potential for drug discovery, it becomes relevant to search for potent, effective and relatively safe plant medicines. Epilepsy …