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Preeclampsia is a disease that occurs in pregnancy after 20 weeks of gestation with manifestations involving multi organ systems such as pulmonary edema and ventricle dysfunction. Cardiomyopathy is a heart disorder characterized by myocardial dysfunction unrelated to any other previous heart disease. Case: A 31-year-old woman diagnosed with G1P0A0 full-term pregnancy, preeclampsia, pulmonary edema, cardiomyopathy, and fetal distress, who underwent cesarean section. On physical examination, shortness of breath was found in semi-Fowler position. Patient had high blood pressure and global hypokinesis was found on echocardiography results. She was planned for general anesthesia with semi-closed intubation technique and breath controlled. Anesthetic management should optimize the preoxygenation, provide positive pressure ventilation with positive end-expiratory pressure (PEEP), maintain the minimal myocardial depressant effect of drugs, and maintain a normovolemic state. It could improve the good outcomes. Conclusion: Three things that must be considered when starting the induction are oxygenation, fluid status, and selection of drugs that do not make the heart work harder. The combination of fentanyl, midazolam, and sevoflurane is the drug of choice used for induction, because it can minimize the cardiac depressant effect.