作者
Manuela Frank, Florian T Gassert, Theresa Urban, Konstantin Willer, Wolfgang Noichl, Rafael Schick, Manuel Schultheiss, Manuel Viermetz, Bernhard Gleich, Fabio De Marco, Julia Herzen, Thomas Koehler, Klaus Jürgen Engel, Bernhard Renger, Felix G Gassert, Andreas Sauter, Alexander A Fingerle, Bernhard Haller, Marcus R Makowski, Daniela Pfeiffer, Franz Pfeiffer
发表日期
2022/11/21
期刊
Communications Medicine
卷号
2
期号
1
页码范围
147
出版商
Nature Publishing Group UK
简介
Background
Currently, alternative medical imaging methods for the assessment of pulmonary involvement in patients infected with COVID-19 are sought that combine a higher sensitivity than conventional (attenuation-based) chest radiography with a lower radiation dose than CT imaging.
Methods
Sixty patients with COVID-19-associated lung changes in a CT scan and 40 subjects without pathologic lung changes visible in the CT scan were included (in total, 100, 59 male, mean age 58 ± 14 years). All patients gave written informed consent. We employed a clinical setup for grating-based dark-field chest radiography, obtaining both a dark-field and a conventional attenuation image in one image acquisition. Attenuation images alone, dark-field images alone, and both displayed simultaneously were assessed for the presence of COVID-19-associated lung changes on a scale from 1 to 6 (1 = surely not, 6 …
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M Frank, FT Gassert, T Urban, K Willer, W Noichl… - Communications Medicine, 2022