作者
Yalcin Solak, Abduzhappar Gaipov, Suleyman Turk, Mehmet Kayrak, Mahmut I Yilmaz, Kayser Caglar, Samet Verim, Hilmi U Unal, Mahmut Gok, Erkan Demirkaya, Hakki Cetinkaya, Tayfun Eyileten, Mutlu Saglam, Abdulgaffar Vural
发表日期
2014/2/1
期刊
The American journal of the medical sciences
卷号
347
期号
2
页码范围
118-124
出版商
Elsevier
简介
Background
Red cell distribution width (RDW) is a measure of erythrocyte size variability and has been shown as an independent predictor of mortality. The aim of this article was to evaluate the association of RDW with endothelial dysfunction in patients with chronic kidney disease (CKD).
Methods
Patients with 1 to 5 stages of CKD were included in the study. Endothelial function was assessed with flow-mediated dilatation (FMD). Estimated glomerular filtration rate (eGFR) and carotid intima media thickness (CIMT) were determined. Clinicode-mographic characteristics, biochemical values, complete blood counts, ferritin, C-reactive protein (CRP) and cholesterol levels were recorded. Spearman's correlation was used to determine correlates of RDW. Multivariate linear regression model was used to assess independent associates of FMD.
Results
Overall, 367 patients with CKD 1 to 5 were included in the study. RDW …
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