作者
Guy Young, Manuela Albisetti, Mariana Bonduel, Leonardo Brandao, Anthony Chan, Frauke Friedrichs, Neil A Goldenberg, Eric Grabowski, Christine Heller, Janna Journeycake, Gili Kenet, Anne Krümpel, Karin Kurnik, Aaron Lubetsky, Christoph Male, Marilyn Manco-Johnson, Prasad Mathew, Paul Monagle, Heleen van Ommen, Paolo Simioni, Pavel Svirin, Daniela Tormene, Ulrike Nowak-Göttl
发表日期
2008/9/23
期刊
Circulation
卷号
118
期号
13
页码范围
1373-1382
出版商
Lippincott Williams & Wilkins
简介
Background— The aim of the present study was to estimate the impact of inherited thrombophilia (IT) on the risk of venous thromboembolism (VTE) onset and recurrence in children by a meta-analysis of published observational studies.
Methods and Results— A systematic search of electronic databases (Medline, EMBASE, OVID, Web of Science, The Cochrane Library) for studies published from 1970 to 2007 was conducted using key words in combination as both MeSH terms and text words. Citations were independently screened by 2 authors, and those meeting the inclusion criteria defined a priori were retained. Data on year of publication, study design, country of origin, number of patients/controls, ethnicity, VTE type, and frequency of recurrence were abstracted. Heterogeneity across studies was evaluated, and summary odds ratios and 95% CIs were calculated with both fixed-effects and random-effects …
引用总数
学术搜索中的文章
G Young, M Albisetti, M Bonduel, L Brandao, A Chan… - Circulation, 2008