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Reproductive efficiency of animals lies on their potency in discharging their reproductive functions, which however borders on the ability to procreate. For instance, in male animals, if spermatogenesis pathway is truncated by any genetic, physiological or hormonal factor, efficiency in reproduction is drastically hampered. Several plants have been identified to possess anti-fertility or contraceptive property (Udoh and Kehinde, 1999) Carica papaya from the family of caricaceae is a perennial, seed propagated plant, which originated from Central America but now found everywhere. It is a plant that has been economically exploited The fruits, leaves, latex, roots and seeds contains novel biologically active compounds Such as saponin, glycoside, polyphenol, carpaine, tannin, papain, flavanols, alkaloids, qunions, etc (Franco et al., 1993; Udoh and Udoh, 2005) These bioactive compounds have been exploited …