作者
Till Keller, Tanja Zeller, Francisco Ojeda, Stergios Tzikas, Lars Lillpopp, Christoph Sinning, Philipp Wild, Sabine Genth-Zotz, Ascan Warnholtz, Evangelos Giannitsis, Martin Möckel, Christoph Bickel, Dirk Peetz, Karl Lackner, Stephan Baldus, Thomas Münzel, Stefan Blankenberg
发表日期
2011/12/28
期刊
Jama
卷号
306
期号
24
页码范围
2684-2693
出版商
American Medical Association
简介
Context
Introduction of highly sensitive troponin assays into clinical practice has substantially improved the evaluation of patients with chest pain.
Objective
To evaluate the diagnostic performance of a highly sensitive troponin I (hsTnI) assay compared with a contemporary troponin I (cTnI) assay and their serial changes in the diagnosis of acute myocardial infarction (AMI).
Design, Setting, and Patients
A total of 1818 patients with suspected acute coronary syndrome were consecutively enrolled at the chest pain units of the University Heart Center Hamburg, the University Medical Center Mainz, and the Federal Armed Forces Hospital Koblenz, all in Germany, from 2007 to 2008. Twelve biomarkers including hsTnI (level of detection, 3.4 pg/mL) and cTnI (level of detection, 10 pg/mL) were measured on admission and after 3 and 6 hours.
Main Outcome Measures
Diagnostic performance for AMI of baseline and serial …
学术搜索中的文章
T Keller, T Zeller, F Ojeda, S Tzikas, L Lillpopp… - Jama, 2011