作者
Qiang Zheng, Ingrid A Cox, Lucy Leigh, Barbara de Graaff, Fay H Johnston, Tamera J Corte, Luke D Knibbs, Petr Otahal, Vidya Navaratnam, Julie A Campbell, Ian Glaspole, Yuben Moodley, Peter Hopkins, John A Mackintosh, Hasnat Ahmad, E Haydn Walters, Andrew J Palmer
发表日期
2023/10
期刊
Respirology
卷号
28
期号
10
页码范围
916-924
出版商
John Wiley & Sons, Ltd
简介
Background and Objective
Little is known about the association between ambient air pollution and idiopathic pulmonary fibrosis (IPF) in areas with lower levels of exposure. We aimed to investigate the impact of air pollution on lung function and rapid progression of IPF in Australia.
Methods
Participants were recruited from the Australian IPF Registry (n = 570). The impact of air pollution on changes in lung function was assessed using linear mixed models and Cox regression was used to investigate the association with rapid progression.
Results
Median (25th–75th percentiles) annual fine particulate matter (<2.5 μm, PM2.5) and nitrogen dioxide (NO2) were 6.8 (5.7, 7.9) μg/m3 and 6.7 (4.9, 8.2) ppb, respectively. Compared to living more than 100 m from a major road, living within 100 m was associated with a 1.3% predicted/year (95% confidence interval [CI] −2.4 to −0.3) faster annual decline in diffusing …
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Q Zheng, IA Cox, L Leigh, B de Graaff, FH Johnston… - Respirology, 2023