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The aim of our study was to evaluate whether perirenal fat thickness (PRFT), a parameter of central obesity, is related to carotid intima‐media thickness (IMT), an index of atherosclerosis in human immunodeficiency virus (HIV)‐1‐infected patients.

We enrolled 70 consecutive HIV‐1‐infected patients receiving highly active antiretroviral therapy for more than 12 months, in a prospective cohort study. Sonographically measured PRFT and carotid IMT, as well as serum metabolic parameters, were evaluated. PRFT and IMT were measured using 3.75‐MHz convex and 7.5‐MHz linear probes, respectively.

The mean PRFT and IMT in HIV‐1‐infected patients with visceral obesity was significantly greater than those in patients without it (p < 0.0001 and p < 0.01, respectively). Using the average IMT as the dependent variable in regression analysis, PRFT was an independent factor associated …