作者
JA De Carvalho, MA Beale, F Hagen, MC Fisher, R Kano, A Bonifaz, C Toriello, R Negroni, RS de M Rego, IDF Gremião, SA Pereira, ZP de Camargo, AM Rodrigues
发表日期
2021/9/1
期刊
Studies in mycology
卷号
100
页码范围
100129
出版商
No longer published by Elsevier
简介
Sporothrix (Ophiostomatales) comprises species that are pathogenic to humans and other mammals as well as environmental fungi. Developments in molecular phylogeny have changed our perceptions about the epidemiology, host-association, and virulence of Sporothrix. The classical agent of sporotrichosis, Sporothrix schenckii, now comprises several species nested in a clinical clade with S. brasiliensis, S. globosa, and S. luriei. To gain a more precise view of outbreaks dynamics, structure, and origin of genetic variation within and among populations of Sporothrix, we applied three sets of discriminatory AFLP markers (#3 EcoRI-GA/MseI-TT, #5 EcoRI-GA/MseI-AG, and #6 EcoRI-TA/MseI-AA) and mating-type analysis to a large collection of human, animal and environmental isolates spanning the major endemic areas. A total of 451 polymorphic loci were amplified in vitro from 188 samples, and revealed high …
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JA De Carvalho, MA Beale, F Hagen, MC Fisher… - Studies in mycology, 2021