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By the late fifteenth century, the debate over the role of reason and the constitution of the human subject freed public discourse from its reliance on God and placed the rational individual at the centre of social and political thought. The emphasis on rationality necessitated a parallel discourse on its opposite—‘reason’s Other'. In this period, representations of disabled people change in response to this new paradigm. Late medieval cultural documents, such as those of Brant and Bosch, employ folly as a metaphorical device, associated with the qualities of Everyman. However, with the rise of renaissance humanism, the benign metaphors of folly associated with the abstract everyman quickly become inscribed on the bodies of those people who would be constructed as reason's ‘Other’—people with intellectual and physical disabilities—and the abstract discourse of folly is transformed into a much more direct …