作者
Camilla J Williams, Mark G Williams, Nir Eynon, Kevin J Ashton, Jonathan P Little, Ulrik Wisloff, Jeff S Coombes
发表日期
2017/11
来源
BMC genomics
卷号
18
页码范围
81-110
出版商
BioMed Central
简介
Background
Cardiorespiratory fitness (VO2max) is an excellent predictor of chronic disease morbidity and mortality risk. Guidelines recommend individuals undertake exercise training to improve VO2max for chronic disease reduction. However, there are large inter-individual differences between exercise training responses. This systematic review is aimed at identifying genetic variants that are associated with VO2max trainability.
Methods
Peer-reviewed research papers published up until October 2016 from four databases were examined. Articles were included if they examined genetic variants, incorporated a supervised aerobic exercise intervention; and measured VO2max/VO2peak pre and post-intervention.
Results
Thirty-five articles describing 15 cohorts met the criteria for inclusion. The majority of studies used a …
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