作者
Ming-Ting Wu, Wen-Yih I Tseng, Mao-Yuan M Su, Chun-Peng Liu, Kuan-Rau Chiou, Van J Wedeen, Timothy G Reese, Chien-Fang Yang
发表日期
2006/9/5
期刊
Circulation
卷号
114
期号
10
页码范围
1036-1045
出版商
Lippincott Williams & Wilkins
简介
Background— Diffusion tensor magnetic resonance imaging (DT-MRI) provides a means for nondestructive characterization of myocardial architecture. We used DT-MRI to investigate changes in direction-dependent water diffusivity to reflect alterations in tissue integrity (trace apparent diffusion coefficients [ADCs] and fractional anisotropy [FA]), as well as indicators of remodeling of fiber helix angles, in patients after myocardial infarction.
Methods and Results— Thirty-seven patients (35 men, 2 women; median age, 59) after acute myocardial infarction (median interval from onset, 26 days) were enrolled. DT-MRI was performed at the midventricular level to measure trace ADC, FA, and helix angles of myofibers. Helix angles were grouped into left-handed helical fibers, circumferential fibers, and right-handed helical fibers. Measurements were correlated with viability and regional wall motion assessed by contrast …
引用总数
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MT Wu, WYI Tseng, MYM Su, CP Liu, KR Chiou… - Circulation, 2006