作者
Douglas Barthold, Elizabeth Brouwer, Lee J Barton, David E Arterburn, Anirban Basu, Anita Courcoulas, Cecelia L Crawford, Peter N Fedorka, Heidi Fischer, Benjamin B Kim, Edward C Mun, Sameer B Murali, Kristi Reynolds, Tae K Yoon, Robert E Zane, Karen J Coleman
发表日期
2022/1/1
期刊
Diabetes Care
卷号
45
期号
1
页码范围
92-99
出版商
American Diabetes Association
简介
OBJECTIVE
There are few studies testing the amount of weight loss necessary to achieve initial remission of type 2 diabetes mellitus (T2DM) following bariatric surgery and no published studies with use of weight loss to predict initial T2DM remission in sleeve gastrectomy (SG) patients.
RESEARCH DESIGN AND METHODS
With Cox proportional hazards models we examined the relationship between initial T2DM remission and percent total weight loss (%TWL) after bariatric surgery. Categories of %TWL were included in the model as time-varying covariates.
RESULTS
Of patients (N = 5,928), 73% were female; mean age was 49.8 ± 10.3 years and BMI 43.8 ± 6.92 kg/m2, and 57% had Roux-en-Y gastric bypass (RYGB). Over an average follow-up of 5.9 years, 71% of patients experienced initial remission of T2DM (mean time to remission 1.0 year). With 0–5 …
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D Barthold, E Brouwer, LJ Barton, DE Arterburn… - Diabetes Care, 2022