作者
Chukwuebuka Egbuna, Vijaykumar K Parmar, Jaison Jeevanandam, Shahira M Ezzat, Kingsley C Patrick-Iwuanyanwu, Charles Oluwaseun Adetunji, Johra Khan, Eugene N Onyeike, Chukwuemelie Zedech Uche, Muhammad Akram, Mervat S Ibrahim, Nihal M El Mahdy, Chinaza Godswill Awuchi, Kaliyaperumal Saravanan, Habibu Tijjani, Uchenna Estella Odoh, Mohammed Messaoudi, Jonathan C Ifemeje, Michael C Olisah, Nebechi Jane Ezeofor, Chukwudi Jude Chikwendu, Chinwe Gloria Ibeabuchi
发表日期
2021/1/1
来源
Journal of Toxicology
卷号
2021
期号
1
页码范围
9954443
出版商
John Wiley & Sons, Ltd
简介
Nanoparticles are of great importance in development and research because of their application in industries and biomedicine. The development of nanoparticles requires proper knowledge of their fabrication, interaction, release, distribution, target, compatibility, and functions. This review presents a comprehensive update on nanoparticles’ toxic effects, the factors underlying their toxicity, and the mechanisms by which toxicity is induced. Recent studies have found that nanoparticles may cause serious health effects when exposed to the body through ingestion, inhalation, and skin contact without caution. The extent to which toxicity is induced depends on some properties, including the nature and size of the nanoparticle, the surface area, shape, aspect ratio, surface coating, crystallinity, dissolution, and agglomeration. In all, the general mechanisms by which it causes toxicity lie on its capability to initiate the …
引用总数
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