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Total mercury (Hg) concentrations were determined in fillet tissue of sport fish captured in the Sacramento–San Joaquin River Delta and surrounding tributaries, a region particularly impacted by historic gold and mercury mining activity. In 1999 and 2000, mercury concentrations were measured in 767 samples from ten fish species. Largemouth bass (Micropterus salmoides), the primary target species, exhibited a median Hg concentration of 0.53 μg g⁻¹ (N=406). Only 23 largemouth bass (6%) were below a 0.12 μg g⁻¹ threshold corresponding to a 4 meals per month safe consumption limit. Most of the largemouth bass (222 fish, or 55% of the sample) were above a 0.47 μg g⁻¹ threshold corresponding to a 1 meal per month consumption limit. Striped bass (Morone saxatilis), channel catfish (Ictalurus punctatus), white catfish (Ameirus catus), and Sacramento pikeminnow (Ptychocheilus grandis) also had relatively …