作者
Elizabeth L Whitlock, L Grisell Diaz-Ramirez, M Maria Glymour, W John Boscardin, Kenneth E Covinsky, Alexander K Smith
发表日期
2017/8/1
期刊
JAMA internal medicine
卷号
177
期号
8
页码范围
1146-1153
出版商
American Medical Association
简介
Importance
Chronic pain is common among the elderly and is associated with cognitive deficits in cross-sectional studies; the population-level association between chronic pain and longitudinal cognition is unknown.
Objective
To determine the population-level association between persistent pain, which may reflect chronic pain, and subsequent cognitive decline.
Design, Setting, and Participants
Cohort study with biennial interviews of 10 065 community-dwelling older adults in the nationally representative Health and Retirement Study who were 62 years or older in 2000 and answered pain and cognition questions in both 1998 and 2000. Data analysis was conducted between June 24 and October 31, 2016.
Exposures
“Persistent pain,” defined as a participant reporting that he or she was often troubled with moderate or severe pain in both the 1998 and 2000 interviews.
Main Outcomes and Measures
Coprimary …
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