作者
Christoph J Laux, Gundula Berzaczy, Michael Weber, Susanna Lang, Martin Dominkus, Reinhard Windhager, Iris-Melanie Nöbauer-Huhmann, Philipp T Funovics
发表日期
2015/1
期刊
International orthopaedics
卷号
39
页码范围
97-104
出版商
Springer Berlin Heidelberg
简介
Purpose
This study evaluated the feasibility of computed magnetic resonance imaging (MRI) volumetry in conventional osteosarcomas. Secondly, we investigated whether computed volumetry provides new prognostic indicators for histological response of osteosarcomas after neoadjuvant chemotherapy.
Methods
In a retrospective cohort study, data from the Vienna Bone Tumour Registry was used. MR images from 14 patients (male:female = 1.8, mean age 19 years) were analysed prior to and after neoadjuvant chemotherapy according to current therapy regimens. Histological response to chemotherapy was graded according to the Salzer-Kuntschik classification. Computed volumetry was performed for the intraosseous part, as well as the soft-tissue component and the tumour as a whole.
Results
In a setting of …
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