作者
A Esrafilian, L Stenroth, ME Mononen, P Tanska, J Avela, RK Korhonen
发表日期
2020/2/20
期刊
Scientific reports
卷号
10
期号
1
页码范围
3026
出版商
Nature Publishing Group UK
简介
Abnormal mechanical loading is essential in the onset and progression of knee osteoarthritis. Combined musculoskeletal (MS) and finite element (FE) modeling is a typical method to estimate load distribution and tissue responses in the knee joint. However, earlier combined models mostly utilize static-optimization based MS models and muscle force driven FE models typically use elastic materials for soft tissues or analyze specific time points of gait. Therefore, here we develop an electromyography-assisted muscle force driven FE model with fibril-reinforced poro(visco)elastic cartilages and menisci to analyze knee joint loading during the stance phase of gait. Moreover, since ligament pre-strains are one of the important uncertainties in joint modeling, we conducted a sensitivity analysis on the pre-strains of anterior and posterior cruciate ligaments (ACL and PCL) as well as medial and lateral collateral ligaments …
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A Esrafilian, L Stenroth, ME Mononen, P Tanska… - Scientific reports, 2020