作者
José G Montoya, Amy E Adams, Valérie Bonetti, Sien Deng, Nan A Link, Suzanne Pertsch, Kjerstie Olson, Martina Li, Ellis C Dillon, Dominick L Frosch
发表日期
2021/11
期刊
Microbiology Spectrum
卷号
9
期号
3
页码范围
e01162-21
出版商
American Society for Microbiology
简介
Studies examining antibody responses by vaccine brand are lacking and may be informative for optimizing vaccine selection, dosage, and regimens. The purpose of this study is to assess IgG antibody responses following immunization with BNT162b2 (30 μg mRNA) and mRNA-1273 (100 μg mRNA) vaccines. A cohort of clinicians at a nonprofit organization is being assessed clinically and serologically following immunization with BNT162b2 or mRNA-1273. IgG responses were measured at the Remington Laboratory by an IgG assay against the SARS-CoV-2 spike protein-receptor binding domain. Mixed-effect linear (MEL) regression modeling was used to examine whether the SARS-CoV-2 IgG level differed by vaccine brand, dosage, or number of days since vaccination. Among 532 SARS-CoV-2 seronegative participants, 530 (99.6%) seroconverted with either vaccine. After adjustments for age and gender …
引用总数
学术搜索中的文章