作者
Maurizio Gasparini, Angelo Auricchio, François Regoli, Cecilia Fantoni, Mihoko Kawabata, Paola Galimberti, Daniela Pini, Carlo Ceriotti, Edoardo Gronda, Catherine Klersy, Simona Fratini, Helmut H Klein
发表日期
2006/8/15
期刊
Journal of the American College of Cardiology
卷号
48
期号
4
页码范围
734-743
出版商
American College of Cardiology Foundation
简介
Objectives
The goal of this study was to investigate the effects of cardiac resynchronization therapy (CRT) in heart failure patients with permanent atrial fibrillation (AF) and the role of atrioventricular junction (AVJ) ablation.
Background
Cardiac resynchronization therapy has been proven effective in heart failure patients with sinus rhythm (SR). However, little is known about the effects of CRT in heart failure patients with permanent AF.
Methods
Efficacy of CRT on ventricular function, exercise performance, and reversal of maladaptive remodeling process was prospectively compared in 48 patients with permanent AF in whom ventricular rate was controlled by drugs, thus resulting in apparently adequate delivery of biventricular pacing (>85% of pacing time), and in 114 permanent AF patients, who had undergone AVJ ablation (100% of resynchronization therapy delivery). The clinical and echocardiographic long-term …
引用总数
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M Gasparini, A Auricchio, F Regoli, C Fantoni… - Journal of the American College of Cardiology, 2006