作者
Udaya Seneviratne, Mark Cook, Wendyl D’Souza
发表日期
2012/2
来源
Epilepsia
卷号
53
期号
2
页码范围
234-248
出版商
Blackwell Publishing Ltd
简介
Idiopathic generalized epilepsy (IGE) is classified into several subsyndromes based on clinical and electroencephalography (EEG) features. The EEG signature of IGE is bisynchronous, symmetric, and generalized spike‐wave complex; although focal, irregular, and so called “fragments” of discharges are not uncommon. Other characteristic EEG features include polyspikes, polyspike‐wave discharges, occipital intermittent rhythmic delta activity, and photoparoxysmal response. Both human and animal data suggest involvement of the thalamus and the cortex in the generation of spike‐wave discharges in IGE. Circadian variations of generalized epileptiform discharges are well described, and these can be useful in diagnostic confirmation. Those discharges tend to occur more often after awakening and during cyclic alternating pattern phase‐A of non–rapid eye movement sleep. Activation procedures such as …
学术搜索中的文章
U Seneviratne, M Cook, W D'Souza - Epilepsia, 2012