作者
Peter Fong, Raghav Wusirika, Jose Rueda, Kalani L Raphael, Shehzad Rehman, Megan Stack, Angelo de Mattos, Renu Gupta, Kendall Michels, Firas G Khoury, Vanderlene Kung, Nicole K Andeen
发表日期
2022/12/1
期刊
Kidney International Reports
卷号
7
期号
12
页码范围
2608-2616
出版商
Elsevier
简介
Introduction
Causes of secondary oxalate nephropathy include enteric dysfunction and excessive intake of oxalate or oxalate precursors. During the COVID-19 pandemic, there has been a dramatic rise in sales of supplements and vitamin C, during which time we observed an apparent increase in the proportion of ingestion-associated oxalate nephropathy.
Methods
We retrospectively reviewed secondary oxalate nephropathy and compared pre-pandemic (2018–2019) and pandemic (2020–early 2022) time periods.
Results
We identified 35 patients with kidney biopsy proven (30 native, 5 allograft) oxalate nephropathy at a single academic institution. Supplement-associated oxalate nephropathy comprised a significantly higher proportion of cases during COVID-19 pandemic compared with the preceding 2 years (44% vs. 0%, P = 0.002), and was associated with use of vitamin C, dietary changes, and supplements …
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P Fong, R Wusirika, J Rueda, KL Raphael, S Rehman… - Kidney International Reports, 2022