作者
Sandra S Negro, Emilie J Millet, Delphine Madur, Cyril Bauland, Valérie Combes, Claude Welcker, François Tardieu, Alain Charcosset, Stéphane D Nicolas
发表日期
2019/12
期刊
BMC plant biology
卷号
19
页码范围
1-22
出版商
BioMed Central
简介
Background
Single Nucleotide Polymorphism (SNP) array and re-sequencing technologies have different properties (e.g. calling rate, minor allele frequency profile) and drawbacks (e.g. ascertainment bias). This lead us to study their complementarity and the consequences of using them separately or combined in diversity analyses and Genome-Wide Association Studies (GWAS). We performed GWAS on three traits (grain yield, plant height and male flowering time) measured in 22 environments on a panel of 247 F1 hybrids obtained by crossing 247 diverse dent maize inbred lines with a same flint line. The 247 lines were genotyped using three genotyping technologies (Genotyping-By-Sequencing, Illumina Infinium 50 K and Affymetrix Axiom 600 K arrays).
Results
The effects of ascertainment bias of the 50 K and 600 K arrays were negligible for …
引用总数
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