作者
H Li, L Deng, HX Bai, J Sun, Y Cao, Y Tao, MD Farwell, P Zhang, B Xiao, L Yang
发表日期
2018/2/1
来源
American Journal of Neuroradiology
卷号
39
期号
2
页码范围
280-288
出版商
American Journal of Neuroradiology
简介
BACKGROUND
Current studies that analyze the usefulness of amino acid and FDG-PET in distinguishing brain metastasis recurrence and radionecrosis after radiation therapy are limited by small cohort size.
PURPOSE
Our aim was to assess the diagnostic accuracy of amino acid and FDG-PET in differentiating brain metastasis recurrence from radionecrosis after radiation therapy.
DATA SOURCES
Studies were retrieved from PubMed, Embase, and the Cochrane Library.
STUDY SELECTION
Fifteen studies were included from the literature. Each study used PET to differentiate radiation necrosis from tumor recurrence in contrast-enhancing lesions on follow-up brain MR imaging after treating brain metastasis with radiation therapy.
DATA ANALYSIS
Data were analyzed with a bivariate random-effects model. Sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio were pooled …
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H Li, L Deng, HX Bai, J Sun, Y Cao, Y Tao, MD Farwell… - American Journal of Neuroradiology, 2018