作者
Ervin R Fox, J Hunter Young, Yali Li, Albert W Dreisbach, Brendan J Keating, Solomon K Musani, Kiang Liu, Alanna C Morrison, Santhi Ganesh, Abdullah Kutlar, Vasan S Ramachandran, Josef F Polak, Richard R Fabsitz, Daniel L Dries, Deborah N Farlow, Susan Redline, Adebowale Adeyemo, Joel N Hirschorn, Yan V Sun, Sharon B Wyatt, Alan D Penman, Walter Palmas, Jerome I Rotter, Raymond R Townsend, Ayo P Doumatey, Bamidele O Tayo, Thomas H Mosley Jr, Helen N Lyon, Sun J Kang, Charles N Rotimi, Richard S Cooper, Nora Franceschini, J David Curb, Lisa W Martin, Charles B Eaton, Sharon LR Kardia, Herman A Taylor, Mark J Caulfield, Georg B Ehret, Toby Johnson, International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS), Patricia B Munroe, Kenneth M Rice, Murielle Bochud, Andrew D Johnson, Daniel I Chasman, Albert V Smith, Martin D Tobin, Germaine C Verwoert, Shih-Jen Hwang, Vasyl Pihur, Peter Vollenweider, Paul F O'Reilly, Najaf Amin, Jennifer L Bragg-Gresham, Alexander Teumer, Nicole L Glazer, Lenore Launer, Jing Hua Zhao, Yurii Aulchenko, Simon Heath, Siim Sõber, Afshin Parsa, Jian'an Luan, Pankaj Arora, Abbas Dehghan, Feng Zhang, Gavin Lucas, Andrew A Hicks, Anne U Jackson, John F Peden, Toshiko Tanaka, Sarah H Wild, Igor Rudan, Wilmar Igl, Yuri Milaneschi, Alex N Parker, Cristiano Fava, John C Chambers, Meena Kumari, Min JinGo, Pim van der Harst, Wen Hong Linda Kao, Marketa Sjögren, DG Vinay, Myriam Alexander, Yasuharu Tabara, Sue Shaw-Hawkins, Peter H Whincup, Yongmei Liu, Gang Shi, Johanna Kuusisto, Mark Seielstad, Xueling Sim, Khanh-Dung Hoang Nguyen, Terho Lehtimäki, Giuseppe Matullo, Ying Wu, Tom R Gaunt, N Charlotte Onland-Moret, Matthew N Cooper, Carl GP Platou, Elin Org, Rebecca Hardy, Santosh Dahgam, Jutta Palmen, Veronique Vitart, Peter S Braund, Tatiana Kuznetsova, Cuno SPM Uiterwaal, Harry Campbell, Barbara Ludwig, Maciej Tomaszewski, Ioanna Tzoulaki, Nicholette D Palmer, CARDIoGRAM consortium, CKDGen consortium, KidneyGen consortium, EchoGen consortium, CHARGE-HF consortium, Thor Aspelund, Melissa Garcia, Yen-Pei C Chang, Jeffrey R O'Connell, Nanette I Steinle, Diederick E Grobbee, Dan E Arking, Dena Hernandez, Samer Najjar, Wendy L McArdle, David Hadley, Morris J Brown, John M Connell, Aroon D Hingorani, Ian NM Day, Debbie A Lawlor, John P Beilby, Robert W Lawrence, Robert Clarke, Rory Collins, Jemma C Hopewell, Halit Ongen, Joshua C Bis, Mika Kähönen, Jorma Viikari, Linda S Adair, Nanette R Lee, Ming-Huei Chen, Matthias Olden, Cristian Pattaro
发表日期
2011/6/1
期刊
Human molecular genetics
卷号
20
期号
11
页码范围
2273-2284
出版商
Oxford University Press
简介
The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA. Among people of European descent, GWASs have identified genetic variants at 13 loci that are associated with blood pressure. It is unknown if these variants confer susceptibility in people of African ancestry. Here, we examined genome-wide and candidate gene associations with systolic blood pressure (SBP) and diastolic blood pressure (DBP) using the Candidate Gene Association Resource (CARe) consortium consisting of 8591 AAs. Genotypes included genome-wide single-nucleotide polymorphism (SNP) data utilizing the Affymetrix 6.0 array with imputation to 2.5 million HapMap SNPs and candidate gene SNP data utilizing a 50K cardiovascular gene-centric array (ITMAT-Broad-CARe [IBC] array). For Affymetrix data, the strongest …
学术搜索中的文章
ER Fox, JH Young, Y Li, AW Dreisbach, BJ Keating… - Human molecular genetics, 2011