作者
Thomas M Kessler, David La Framboise, Sven Trelle, Clare J Fowler, Gustav Kiss, Jürgen Pannek, Brigitte Schurch, Karl-Dietrich Sievert, Daniel S Engeler
发表日期
2010/12/1
来源
European urology
卷号
58
期号
6
页码范围
865-874
出版商
Elsevier
简介
CONTEXT
Treatment of neurogenic lower urinary tract dysfunction (LUTD) is a challenge, because conventional therapies often fail. Sacral neuromodulation (SNM) has become a well-established therapy for refractory non-neurogenic LUTD, but its value in patients with a neurologic cause is unclear.
OBJECTIVE
To assess the efficacy and safety of SNM for neurogenic LUTD.
EVIDENCE ACQUISITION
Studies were identified by electronic search of PubMed, EMBASE, and ScienceDirect (on 15 April 2010) and hand search of reference lists and review articles. SNM articles were included if they reported on efficacy and/or safety of tested and/or permanently implanted patients suffering from neurogenic LUTD. Two reviewers independently selected studies and extracted data. Study estimates were pooled using Bayesian random-effects meta-analysis.
EVIDENCE SYNTHESIS
Of the 26 independent studies (357 …
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