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During the COVID-19 pandemic, social distancing restrictions required courses to be offered fully online, which impacted multidisciplinary courses/events worldwide. The quality of education especially in events relying on in-person activities to convey information quicker than online activities. We have developed a fully-online biophotonics workshop (BW) integrating webinars, at-home experiments, and computer simulations to meet needs of undergraduate students with diverse backgrounds and learning styles. >91.7%, >70%, and >90% of feedback responses were “Very good” and “Good” regarding overall learning, co-ordination and quality of subject matter of BW activities. Other biophotonics/biomedical optics courses may benefit from using similar resources and educational strategies.