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The aim of present review is to establish the use of plants, plant parts or extract in curing Diabetes mellitus. It also collates available data on plants with hypoglycemic effects. In the present investigation, interest is focused on experimental studies performed on hypoglycemic plants and their bioactive components. A brief description is given about the, type of diabetes, related physiological disorders and available herbal plants which can be further exploited for antidiabetic activity. Overall, this review presents the profiles of plants with hypoglycemic properties, reported in the literature.