作者
Rondla Rohini, Kanne Shanker, P Muralidhar Reddyb, Vadde Ravinder
发表日期
2010
期刊
J. Braz. Chem. Soc
卷号
21
期号
1
页码范围
49-57
简介
A series of 6-arylbenzimidazo[1,2-c]quinazoline compounds (11-20) were synthesised by the condensation of 2-(o-aminophenyl)benzimidazole with different arylaldehydes, followed by oxidative cyclisation of the resulting 2-o-arylideneaminophenylbenzimidazoles (1-10). All the products were characterized via IR, ¹H NMR, 13C NMR, MS and elemental analysis. The antimicrobial activities of all 6-arylbenzimidazo [1,2-c]quinazolines against three Gram-positive (S. aureus, B. subtilis, S. pyogenes), three Gram-negative (S. typhimurium, E. coli, K. pneumonia) bacteria and three fungal strains (A. niger, C. albicans, T. viridae) were evaluated. Among the compounds tested 13, 19 and 20 showed most potent inhibitory action against test organisms.
学术搜索中的文章
R Rohini, K Shanker, PM Reddy, V Ravinder - Journal of the Brazilian Chemical Society, 2010