作者
Mary Jo B Lund, Ebonee N Butler, Harvey L Bumpers, Joel Okoli, Monica Rizzo, Nadjo Hatchett, Victoria L Green, Otis W Brawley, Gabriela M Oprea‐Ilies, Sheryl GA Gabram
发表日期
2008/8/1
期刊
Cancer: Interdisciplinary International Journal of the American Cancer Society
卷号
113
期号
3
页码范围
608-615
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
BACKGROUND
A disparate proportion of breast cancer deaths occur among young women, those of African‐American (AA) ancestry, and particularly young AA women. Estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptor‐2 (HER‐2) are key clinically informative biomarkers. The triple‐negative (ER‐/PR‐/HER‐2‐) tumor subgroup is intrinsically resistant to treatment and portends a poor prognosis. Age, race, and socioeconomic status have been associated with triple‐negative tumors (TNT). In the current study, the authors investigated breast cancer subgroups among patients in an urban cancer center serving a multiracial, low socioeconomic population.
METHODS
This case series analyzed female invasive breast cancers diagnosed and/or treated between 2003 and 2004 in the AVON Comprehensive Breast Center at Grady Hospital in Atlanta, Georgia. Data were …
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MJB Lund, EN Butler, HL Bumpers, J Okoli, M Rizzo… - Cancer: Interdisciplinary International Journal of the …, 2008