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According to different views in information systems and the socio-technical perspective, many organizations was led to redefine their business with a more focused IT solutions, this study suggested a number of confirmatory measurement models that establish the ground for the hypothesed research constructs, and utilized the structural equation modeling techniques to test and validate the research hypotheses. The research present the results of a practical investigation of the influence and the effect of enterprise systems role applications and organizational knowledge capabilities on IT governance practices by enhancing its application and usability within the organization. The study suggests that smart enterprise systems capabilities (infrastructure scalability, planning alignments, and HR planning and professional capabilities the IT staff) and knowledge organizational capabilities (individual, managerial, and …