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Eggshell waste belongs to the most abundant natural waste in nature and is created in huge amounts by everyday consumption of eggs. The majority of this material is being discarded, despite the fact that it has multidisciplinary applications. In this review, the possibility of utilizing the method of ball milling to further broaden the application potential of this material is discussed. The particular application fields include the formation of nanophases, bioceramics synthesis, formation of composites and preparation of material with increased sorption ability. In addition, some other specific applications, like the utilization of ball-milled eggshell as a drug delivery agent, or for the formation of antibacterially active species, are also mentioned. The review provides a critical mechanochemical insight into this topic and aims to emphasize the green and sustainable way of utilizing eggshell waste by environmentally friendly method.