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The ability to move freely and to connect with others through communication is invaluable for human independence. In this thesis, we explore how brain-machine interfaces (BMIs) can help patients affected by movement or speech deficits to recover lost human experiences. This work builds on previous findings indicating that premotor and posterior parietal areas are involved in movement generation and language processes. These higher-level brain areas do not only engage in movement execution, but also during planning, representing rich behavioral patternsthat can be leveraged for BMI applications. In this work, we investigated how the ventral premotor cortex (PMv), the posterior parietal cortex (PPC), and the sensorimotor cortex (S1) represent grasp and speech processes at a single-neuron level. Using multielectrode Utah arrays, neuronal populations were recorded in tetraplegic human participants. We …