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This study aimed to compare the force (F)–velocity (v)–power (P)–time (t) relationships of female and male world‐class sprinters. A total of 100 distance–time curves (50 women and 50 men) were computed from international 100‐m finals, to determine the acceleration and deceleration phases of each race: (a) mechanical variables describing the velocity, force, and power output; and (b) F‐P‐v relationships and associated maximal power output, theoretical force and velocity produced by each athlete (P_max, F₀, and V₀). The results showed that the maximal sprint velocity (V_max) and mean power output (W/kg) developed over the entire 100 m strongly influenced 100‐m performance (r > −0.80; P ≤ 0.001). With the exception of mean force (N/kg) developed during the acceleration phase or during the entire 100 m, all of the mechanicals variables observed over the race were greater in men. Shorter acceleration and …