作者
Michael Bezuhly, Claire Temple, Leif J Sigurdson, Roger B Davis, Gordon Flowerdew, E Francis Cook Jr
发表日期
2009/10/15
期刊
Cancer
卷号
115
期号
20
页码范围
4648-4654
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
BACKGROUND
Although immediate breast reconstruction is increasingly offered as part of postmastectomy psychosocial rehabilitation, concerns remain that it may delay adjuvant therapy or impair detection of local recurrence. No single population‐based study has examined the relationship between immediate breast reconstruction and breast cancer‐specific survival.
METHODS
By using data from the US National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) registries, breast cancer‐specific survival was compared for female unilateral mastectomy patients who did or did not undergo immediate breast reconstruction. Cox proportional hazards models were fitted, adjusting for known demographic and disease severity variables and stratifying on reconstruction type (implant or autologous) and age.
RESULTS
Improved breast cancer‐specific survival was observed among all immediate …
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