作者
Lauri A Hicks, Lee H Harrison, Brendan Flannery, James L Hadler, William Schaffner, Allen S Craig, Delois Jackson, Ann Thomas, Bernard Beall, Ruth Lynfield, Arthur Reingold, Monica M Farley, Cynthia G Whitney
发表日期
2007/11/1
期刊
The Journal of infectious diseases
卷号
196
期号
9
页码范围
1346-1354
出版商
The University of Chicago Press
简介
Background. Widespread use of pneumococcal conjugate vaccine (PCV7) resulted in decreases in invasive disease among children and elderly persons. The benefits may be offset by increases in disease due to serotypes not included in the vaccine (hereafter, "nonvaccine serotypes"). We evaluated the effect of PCV7 on incidence of disease due to nonvaccine serotypes.
Methods. Cases of invasive disease were identified in 8 geographic areas through the Centers for Disease Control and Prevention's Active Bacterial Core surveillance. Serotyping and susceptibility testing of isolates were performed. We calculated the incidence of disease for children aged <5 years and adults aged ⩾65 years. We compared rates of serotype-specific disease before and after PCV7 was licensed for use.
Results. The annual incidence of disease due to …
引用总数
学术搜索中的文章
LA Hicks, LH Harrison, B Flannery, JL Hadler… - The Journal of infectious diseases, 2007