作者
Milena Sokolowska, Zuzanna M Lukasik, Ioana Agache, Cezmi A Akdis, Deniz Akdis, Mübeccel Akdis, Weronika Barcik, Helen A Brough, Thomas Eiwegger, Andrzej Eljaszewicz, Stefanie Eyerich, Wojciech Feleszko, Cristina Gomez‐Casado, Karin Hoffmann‐Sommergruber, Jozef Janda, Rodrigo Jiménez‐Saiz, Marek Jutel, Edward F Knol, Inge Kortekaas Krohn, Akash Kothari, Joanna Makowska, Marcin Moniuszko, Hideaki Morita, Liam O'Mahony, Kari Nadeau, Cevdet Ozdemir, Isabella Pali‐Schöll, Oscar Palomares, Francesco Papaleo, Mary Prunicki, Carsten B Schmidt‐Weber, Anna Sediva, Jürgen Schwarze, Mohamed H Shamji, Gerdien A Tramper‐Stranders, Willem van De Veen, Eva Untersmayr
发表日期
2020/10
来源
Allergy
卷号
75
期号
10
页码范围
2445-2476
简介
With the worldwide spread of the novel severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) resulting in declaration of a pandemic by the World Health Organization (WHO) on March 11, 2020, the SARS‐CoV‐2‐induced coronavirus disease‐19 (COVID‐19) has become one of the main challenges of our times. The high infection rate and the severe disease course led to major safety and social restriction measures worldwide. There is an urgent need of unbiased expert knowledge guiding the development of efficient treatment and prevention strategies. This report summarizes current immunological data on mechanisms associated with the SARS‐CoV‐2 infection and COVID‐19 development and progression to the most severe forms. We characterize the differences between adequate innate and adaptive immune response in mild disease and the deep immune dysfunction in the severe multiorgan …
学术搜索中的文章
M Sokolowska, ZM Lukasik, I Agache, CA Akdis… - Allergy, 2020