作者
Zhengnan Huang, Lili Ma, Yongbo Wang, Zhicheng Pan, Jian Ren, Zexian Liu, Yu Xue
发表日期
2015/1/28
期刊
Nucleic acids research
卷号
43
期号
D1
页码范围
D328-D334
出版商
Oxford University Press
简介
We reported an updated database of MiCroKiTS 4.0 (http://microkit.biocuckoo.org) for proteins temporally and spatially localized in distinct subcellular positions including midbody, centrosome, kinetochore, telomere and mitotic spindle during cell division/mitosis. The database was updated from our previously developed database of MiCroKit 3.0, which contained 1489 proteins mostly forming super-complexes at midbody, centrosome and kinetochore from seven eukaryotes. Since the telomere and spindle apparatus are critical for cell division, the proteins localized at the two positions were also integrated. From the scientific literature, we curated 1872 experimentally identified proteins which at least locate in one of the five positions from eight species. Then the ortholog detection was performed to identify potential MiCroKiTS proteins from 144 eukaryotic organisms, which contains 66, 45 and 33 species of …
学术搜索中的文章
Z Huang, L Ma, Y Wang, Z Pan, J Ren, Z Liu, Y Xue - Nucleic acids research, 2015