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The COVID‐19 pandemic introduced mandatory stay‐at‐home orders and concerns about contracting a virus that impacted the physical and mental health of much of the world’s population. This study compared the rates of depression and anxiety in a sample of older primary care patients (aged ≥65 years old) and their family members recruited for a clinical trial before and during the COVID‐19 pandemic. Participants were dyads enrolled in the Caregiver Outcomes of Alzheimer’s Disease Screening (COADS) trial, which included 1,809 dyads of older primary care patients and one of their family members. Mean scores on the Patient Health Questionnaire‐9 (PHQ‐9) and the Generalized Anxiety Disorder Scale‐7 (GAD‐7) were measured and compared before and during the pandemic. We found no difference in depression and anxiety among dyads of older primary care patients and their family members recruited …