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Methods

Patients diagnosed with Stage I NSCLC and treated with either curative surgery, radiation therapy, or ablation from 06/1995-10/2017 at Mayo Clinic in Florida were identified. Through retrospective chart review, data was collected on clinical and demographic features, surveillance imaging, pathology, time to recurrence or second primary lung cancer (SPLC), location of recurrence (loco-regional vs. distant), and treatment of recurrence or SPLC. Kaplan-Meier method was used to evaluate the disease free survival (DFS). Cox proportional hazard model was used to identify prognostic associations.

Results

A total of 271 patients with Stage I NSCLC were included. The majority of patients were treated with surgery (n= 243) compared with radiation therapy or ablation (n= 28). Median time of follow up was 78 months (CI 95% 64-91 months). Of patients who had a recurrence (n= 68), 60 patients (88.2%) recurred …