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Pain in adolescents with cancer (12–18 years) is common and negatively impacts health‐related quality of life (HRQL). The Pain Squad+ smartphone app, which provides adolescents with real‐time pain self‐management support, was developed to address this issue. This study evaluated the implementation of the app to inform a future randomized controlled trial (RCT) and obtain treatment effect estimates for pain intensity, pain interference, HRQL, and self‐efficacy.

A one‐group baseline/poststudy design with 40 adolescents recruited from two pediatric tertiary care centers was used. Baseline questionnaires were completed and adolescents used the app at least twice daily for 28 days, receiving algorithm‐informed self‐management advice depending on their reported pain. A nurse received alerts in response to sustained pain and contacted adolescents to assist in pain care. Poststudy …