作者
Jonathan M Behar, Julian Bostock, ADRIAN PO ZHU LI, Hui Men Selina Chin, Stephen Jubb, Edward Lent, James Gamble, Paul WX Foley, Tim R Betts, Christopher Aldo Rinaldi, Neil Herring
发表日期
2015/5
期刊
Journal of cardiovascular electrophysiology
卷号
26
期号
5
页码范围
540-546
简介
Lower Mortality and Eliminated PNS Associated with Quadripolar Leads
Introduction
Cardiac resynchronization therapy (CRT) using quadripolar left ventricular (LV) leads provides more pacing vectors compared to bipolar leads. This may avoid phrenic nerve stimulation (PNS) and allow optimal lead placement to maximize biventricular pacing. However, a long‐term improvement in patient outcome has yet to be demonstrated.
Methods
A total of 721 consecutive patients with conventional CRTD criteria implanted with quadripolar (n = 357) or bipolar (n = 364) LV leads were enrolled into a registry at 3 UK centers. Lead performance and mortality was analyzed over a 5‐year period.
Results
Patients receiving a quadripolar lead were of similar age and sex to those receiving a bipolar lead, although a lower proportion had ischemic heart disease (62.6% vs. 54.1%, P = 0.02). Both groups had similar rates of …
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