作者
Wendy L Smith, Craig Lewis, Glenn Bauman, George Rodrigues, David D’Souza, Robert Ash, Derek Ho, Varagur Venkatesan, Donal Downey, Aaron Fenster
发表日期
2007/3/15
期刊
International Journal of Radiation Oncology* Biology* Physics
卷号
67
期号
4
页码范围
1238-1247
出版商
Elsevier
简介
Purpose
This study evaluated the reproducibility and modality differences of prostate contouring after brachytherapy implant using three-dimensional (3D) transrectal ultrasound (3DTRUS), T2-weighted magnetic resonance (MR), and computed tomography (CT) imaging.
Methods and Materials
Seven blinded observers contoured 10 patients’ prostates, 30 day postimplant, on 3DTRUS, MR, and CT images to assess interobserver variability. Randomized images were contoured twice by each observer. We analyzed length and volume measurements and performed a 3D analysis of intra- and intermodality variation.
Results
Average volume ratios were 1.16 for CT/MR, 0.90 for 3DTRUS/MR, and 1.30 for CT/3DTRUS. Overall contouring variability was largest for CT and similar for MR and 3DTRUS. The greatest variability of CT contours occurred at the posterior and anterior portions of the midgland. On MR, overall …
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WL Smith, C Lewis, G Bauman, G Rodrigues… - International Journal of Radiation Oncology* Biology …, 2007