作者
Esther Huimin Leow, Jan Hau Lee, Christoph P Hornik, Yong Hong Ng, Thomas Hays, Reese H Clark, Veeral N Tolia, Rachel G Greenberg
发表日期
2023/1
期刊
Pediatric Nephrology
卷号
38
期号
1
页码范围
161-172
出版商
Springer Berlin Heidelberg
简介
Background
The aim of the study was to determine the prevalence of congenital anomalies of the kidney and urinary tract (CAKUT) in the neonatal intensive care unit (NICU) and to evaluate risk factors associated with worse outcomes. We hypothesized that infants with CAKUT with extra-renal manifestations have higher mortality.
Methods
This is a cohort study of all inborn infants who were diagnosed with any form of CAKUT discharged from NICUs managed by the Pediatrix Medical Group from 1997 to 2018. Logistic and linear regression models were used to analyze risk factors associated with in-hospital mortality.
Results
The prevalence of CAKUT was 1.5% among infants hospitalized in 419 NICUs. Among the 13,383 infants with CAKUT analyzed, median gestational age was 35 (interquartile range [IQR] 31–38) weeks and median birth weight was 2.34 (IQR 1.54–3.08) kg. Overall in-hospital mortality for infants …
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EH Leow, JH Lee, CP Hornik, YH Ng, T Hays, RH Clark… - Pediatric Nephrology, 2023