作者
Yvonne C Learmonth, Robert W Motl, Brian M Sandroff, John H Pula, Diego Cadavid
发表日期
2013/12
期刊
BMC neurology
卷号
13
页码范围
1-8
出版商
BioMed Central
简介
Background
The Patient Determined Disease Steps (PDDS) is a promising patient-reported outcome (PRO) of disability in multiple sclerosis (MS). To date, there is limited evidence regarding the validity of PDDS scores, despite its sound conceptual development and broad inclusion in MS research. This study examined the validity of the PDDS based on (1) the association with Expanded Disability Status Scale (EDSS) scores and (2) the pattern of associations between PDDS and EDSS scores with Functional System (FS) scores as well as ambulatory and other outcomes.
Methods
96 persons with MS provided demographic/clinical information, completed the PDDS and other PROs including the Multiple Sclerosis Walking Scale-12 (MSWS-12), and underwent a neurological examination for generating FS and EDSS scores. Participants completed …
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YC Learmonth, RW Motl, BM Sandroff, JH Pula… - BMC neurology, 2013